Hyaluronic acid dermal fillers such as Juvederm, Restylane, Teosyal and Belotero can be dissolved using an enzyme called hyaluronidase. This enzyme is naturally present in our skin, but can be injected in higher concentrations to quickly remove unwanted filler. Hyaluronidase is a soluble protein enzyme that breaks down hyaluronic acid found in dermal fillers. The solution works by disrupting the bonds that hold HA molecules together and encourages the body to reabsorb those molecules in a natural process.
It achieves this by increasing tissue permeability, splitting the molecular bonds that hold hyaluronic acid together and promoting the natural cellular processes responsible for its diffusion. The London Cosmetic Clinic is a dermal filler treatment, dissolution and correction center on Harley Street in central London. In the event of a loss of circulation, the dermal filler must dissolve within 24 hours of the diagnosis of necrosis to save the tissue; otherwise, there is a potential need for a skin graft and surgical intervention to reconstruct the face. If you don't want to wait a year or more for the fill to fade naturally, an expert supplier can improve your results considerably through strategic placement of additional filler.
Often, a small superficial lump on the lip can dissolve quickly, however, larger nodules or extended areas of integration of the filling break down into sections, where one may feel that the filling has disappeared in some areas, while still being seen in others. The enzyme can remove a greater amount of filler than desired, requiring another filler treatment to achieve its original objectives. Hyaluronic acid dermal filler can be dissolved by injecting the hyaluronidase enzyme, which takes 1 to 2 weeks to work. In certain patients, a steroid injection can help reverse the effects of some of these fillers to a certain extent, but the only sure way to “undo the results of these fillers” is to wait for the body to absorb them.
In addition to the new treatment, hyaluronidase can be repeated as soon as 2 days, however, 1 to 2 weeks is recommended to add more dermal filler to a previously dissolved area to ensure that all swelling and injury have resolved and that the patient returns to baseline. Sometimes, when dermal filler is misplaced, incorrectly injected and causes complications, or is over-injected, it is visible to the naked eye. If you're not satisfied with your final results or if you want them to look better, an expert cosmetic surgeon can make corrections or improve the outcome of dermal fillers. Once the filler has completely dissolved and settled after two weeks, you can reinject it into the area correctly and subtly.
In addition, the filler is quite soft and mobile for the first 48 hours after treatment, so there may be some compression of the filler around areas of greatest muscle contraction or if a patient swells much after treatment, this can also cause some compression or movement of the product. If a patient is looking for some aesthetic adjustments and wants to go ahead with dissolution, they should understand that they may also need to replace areas that may have dissolved unevenly with dermal filler.
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